Dr. Singh's Bio-data
Contact Info
Department of Chemistry and Biochemistry
UMass Dartmouth
285 Old Westport Road
North Dartmouth, MA 02747
Telephone: 508-999-8588
Fax : 508-999-8451
Email: BSingh@umassd.edu
Date of Birth
July 25, 1958
Education
- Ph.D (Chemistry, Major-Biophysical Chemistry), 1987, Texas Tech University, Lubbock, TX, U.S.A.
Dissertation title: Molecular topography and binding properties of phytochrome and other related tetrapyrrolic proteins.
- M. Phil (Life Sciences, Major-Biophysical chemistry), 1982.
Jawaharlal Nehru University, New Delhi, India.
Thesis title: Dependence of spectroscopic characteristics of photosynthetic pigments on the organization of chloroplast membranes.
- M. Sc. (Life Sciences, Major-Biochemistry), 1979.
Jawaharlal Nehru University, New Delhi, India.
Thesis title: Biophysical studies of natural and artificial membranes.
- B. Sc. (Chemistry, Biology), 1977.
Kamla Nehru Institute of Science and Technology, Avadh University, Faizabad, India.
Positions held
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DIRECTOR, Botulism Research Center, Univeristy of Massachusetts, Dartmouth (2003-present).
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DIRECTOR, Center for Indic Studies, Univeristy of Massachusetts, Dartmouth (2000-present).
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PROFESSOR, Departments of Chemistry and Biochemistry and Biology. University of Massachusetts, Dartmouth. (1999-present).
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CONSULTING EDITOR, Akhand Bharat Sandesh (monthly newspaper) (2001-present).
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BUREAU CHIEF, United States, Between the Media (a monthly news magazine) (2000-present).
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VISITING ASSOCIATE PROFESSOR, Department of Microbiology and Molecular Genetics
Harvard Medical School (1996-1997).
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ASSOCIATE PROFESSOR, Department of Biology, University of Massachusetts Dartmouth (1997-1999).
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ASSOCIATE PROFESSOR,Department of Chemistry, University of Massachusetts at Dartmouth (1995-1999).
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ASSISTANT PROFESSOR,Department of Chemistry, University of Massachusetts at Dartmouth (1990-1995).
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PROFESSOR, GRADUATE FACULTY, University of Massachusetts at Amherst (February 1992-present)
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VISITING PROFESSOR, Department of Biochemistry, Georgetown University/Center for Bimolecular Science and Engineering, Naval Research Laboratory, Washington, D.C. (June, 1991-August, 1991).
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ASSISTANT SCIENTIST,Environmental Toxicology Center/Department of Food Microbiology and Toxicology, University of Wisconsin-Madison (November 1989-1990).
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ASSOCIATE RESEARCHER, Department of Food Microbiology and Toxicology, UW-Madison (December 1988-October 1989).
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ASSISTANT RESEARCHER, Department of Food Microbiology and Toxicology, UW-Madison (September 1988-November 1988).
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RESEARCH ASSOCIATE, Department of Microbiology and Toxicology, UW-Madison (March 1987-August 1988).
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TEACHING AND RESEARCH ASSISTANT, Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX (1983-1986).
Honors and Awards
· UNIVERSITY SERVICE AWARD,UMass Dartmouth Alumni Assocation, 2004
· NIH Review Panel Biodefense Vaccines, March 5-6, 2003
· Botulinum Neurotoxin Diagnostic Panel, National Institute of Allergy and Infections Diseases, May 23, 2003
· DIRECTOR, Center for Indic Studies, Univeristy of Massachusetts,
· PLENARY SPEAKER, UMass Neuroscience Symposium, June 3, 2002,
· FEATURED FACULTY, UMass Board of Trustees, February 6, 2002.
· COORDINATOR, International Conference on
· SESSION CHAIR, 38th Interagency Botulism Research Coordination Committee Meeting, October 17-19, 2001,
· CHANCELLOR'S INNOVATIVE TEACHING AWARD(2000-2001), UMASS Dartmouth for the course Chemistry of Mind (CHM 550).
· HENRY DREYFUS TEACHER SCHOLAR AWARD (1997).
· Nominated for the
· FACULTY RECOGNITION,
· ASSOCIATE PROFESSOR, Department of Biology, UMass Dartmouth, 1997-present.
· SYMPOSIUM CHAIRMAN, Infrared Analysis of Peptides and Proteins, 216th National Meeting of American Chemical Society,
· GUEST EDITOR, Toxin Reviews, Special Issue on Biochemical and Toxico-Chemical Aspects of Botulinum Neurotoxins, 1997-1998.
· VISITING ASSOCIATE PROFESSORSHIP, Harvard Medical School, 1996-1997.
· UMASS DARTMOUTH FACULTY REPRESENTATIVE TO UMASS BOARD OF TRUSTEES, 1996-1997.
· FEATURED SPEAKER, Symposium on "Chemistry: A Necessary Component of Post Secondary Education" at the 29th Central Regional Meeting of American Chemical Society, May 27030, 1997.
· EDITORIAL BOARD MEMBER (1996-present), Journal of Natural Toxins.
· EDITOR (1996), Natural Toxins 2, Plenum Press,
· SCHOLAR OF THE YEAR AWARD (1995),
· TENURE (1995),
· SYMPOSIUM CHAIRMAN (1995) Natural Toxins, 209th national meeting of Americal Chemical Society,
· CHANCELLOR'S INNOVATIVE TEACHING AWARD, (1995-1996), UMASS Dartmouth.
· PANEL MEMBER (1994), Pew Roundtable on Higher Education, UMass Dartmouth, September 27-28, 1994.
· CHANCELLOR'S INNOVATIVE TEACHING AWARD, (1992-1993), UMASS Dartmouth.
· INVITED PLENARY LECTURE SPEAKER at IVth Pan American Symposium on Animal, Plant and Microbial Toxins,
Topic: Molecular Mechanism of Action of Clostridial Neurotoxins and its Implications to Other Fields.
· COORDINATOR, ROUND TABLE DISCUSSION on "Bacterial Neurotoxins as Scientific and Medical Treasures" at the IVth Pan American Symposium on Animal. Plant and Microbial Toxins,
· YOUNG-INVESTIGATOR GRANT AWARD (1991), National Foundation for Infectious Diseases.
· FACULTY-STAFF DEVELOPMENT TRAVEL AWARD (1989), College of Agricultural and Life Sciences,
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· ROBERT A. WELCH FOUNDATION FELLOWSHIP AWARD,
· SENIOR RESEARCH FELLOWSHIP, Council of Scientific and Industrial Research, Government of
· JUNIOR RESEARCH FELLOWSHIP, Council of Scientific and Industrial Research, Government of
· JUNIOR RESEARCH FELLOWSHIP, Department of Science and Technology project, Government of India (1979-1980).
· UNIVERSITY MERIT SCHOLARSHIP,
· UNIVERSITY MERIT SCHOLARSHIP,
· STATE MERIT SCHOLARSHIP,Ministry of Education,
Invited Seminar/Symposium/Workshop Speaker:
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Department of Chemistry, University of Nebraska-Lincoln (November, 1987).
Topic: Structure-Function Relationship of Botulinum Neurotoxins.
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School of Life Sciences, Jawaharlal Nehru University, New Delhi, India (May, 1989).
Topic: Structure-Function Relationship of Botulinum and Tetanus Neurotoxins.
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National Institute of Immunology, New Delhi, India.
(August, 1989).
Topic: Structure-Function Relationship of Clostridial Neurotoxins.
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A workshop on "Recent Advances in Bioenergetic Processes" Jawaharlal Nehru University, New Delhi, India.
(February, 1990).
Topic: Plant photomorphogenic photoreceptor phytochrome: Molecular Topography and Light Signal Processing.
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Presentation entitled “Structural analysis of botulinum and tetanus neurotoxins using CD and FT-IR spectroscopy” at the Second Asia-Pacific Congress on Animal, Plant and Microbial Toxins, Banaras Hindu University, Varanasi, India, February 19-22, 1990.
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Center for Bio/Molecular Engineering, Naval Research Laboratory, Washington, D.C. (December, 1990)
Topic: Spectroscopic Analysis of Structure-Function Relationship of Biomacromolecules.
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College of Arts and Sciences Food for Thought Seminar Series, Southeastern Massachusetts University
(February, 1991)
Topic: Thou Sword Turned into Plough Share. The Toxins.
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Department of Chemistry, Southeastern Massachusetts University (March, 1991)
Topic: Spectroscopic Analysis of Structure-Function Relationship of Biological Macromolecules.
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Presentation entitled “Molecular differences between botulinum neurotoxin and its toxoid” at the Thitry sixth Interagency Botulism Research Coordination Committee (IBRCC) meeting, December 16-18, 1991, Philadelphia, PA.
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Department of Natural Sciences, Roger Williams College, Bristol, R.I. (December, 1991)
Topic: Thou Sword Turned into Plough share. The Toxins.
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Division of Biology and Medicine, Brown University, Providence, R.I. (February, 1992)
Topic: Structure-Function Relationship of Clostridial Neurotoxins.
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International Conference on Botulinum and Tetanus Neurotoxins: Neurotransmission and Biomedical Aspects, University of Wisconsin, Madison, WI (May 11-13, 1992)
Topic: Comparative Topography of Botulinum and Tetanus Neurotoxins, and its Relationship to Their Function.
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Division of Molecular Biology, Office of Naval Research, Arlington, VA (August 1992)
Topic: Structure-Function Relationship of Biological Macromolecules.
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Presentation entitiled “Immunochemical characterization of botulinum neurotoxin in its purified and complex forms” at the Thitry seventh Interagency Botulism Research Coordination Committee (IBRCC) meeting, December 7-9, 1992, College Park, MD.
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Department of Chemistry, Rhode Island College, Providence. RI (December 1992); Thou Sword Turned into Plow Share: Toxins as Scientific and Medical Tools.
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Industrial Toxicology Research Institute, Lucknow, India (June 1993) Structure-Function Relationship of Botulinum and Tetanus Neurotoxins.
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Presentation entitled “Structure-function relationship of botulinum and tetanus neurotoxins” at theThird Asia Pacific Congress on Animal, Plant, and Microbial Toxins, June 27-July1, 1993, Kuala Lumpur, Malaysia.
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Presentation entitled “Immunochemical properties and detection of botulinum neurotoxins” at the Thirty eighth Interagency Botulism Research Coordination Committee (IBRCC) meeting, November 15-17, 1993, Madison, WI.
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Departments of Chemistry and Biochemistry, University of Massachusetts Amherst, MA (March 1994) Spectroscopic Analysis of Structure-Function Relationship of Bacterial Protein Toxins.
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Department of Microbiology, Biochemistry and Molecular Biology, University of Idaho, ID (April, 1994) Structure-Function Relationship of Bacterial Protein Toxins.
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Presented an invited seminar entitled "Botulinum Neurotoxin and Its Complexing Proteins" at the Toxinology Division, US Army Medical Institute of Infectious Diseases, Ft. Detrick, Frederick, MD, September 19, 1994.
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Presented an invited seminar entitled "Biochemical and Immunological Characterization of Botulinum Neurotoxin and Its Complexing Proteins" at the U.S. Army Edgewood Research, Development and Engineering Center, Aberdeen Proving Ground, MD, September 20, 1994.
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Presentation entitled “Role of Botulinum Complexing Proteins in the Detection of Botulinum Neurotoxins” at the Scientific Conference on Chemical and Biological Defense Research, Aberdeen Proving Ground, U.S.Army, Edgewood, MD, November 15-18, 1994.
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Presented an invited seminar entitled "Thou sword turned into plowshare: the toxins" at the Department of Chemistry, University of Southern Maine, December 8, 1994.
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Presented an invited seminar entitled "Structure-function relationship of clostridial neurotoxins" at the Department of Chemistry, Wesleyan University, March 8, 1995.
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Presentation entitled “Structure-function relationship of bacterial protein toxins” at the 209th National Meeting of American Chemical Society, Anaheim, CA, April 2-6, 1995.
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Presented an invited seminar entitled "Structure and Function of Bacterial Protein Toxins" at the School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, December 26, 1995.
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Presented an invited seminar entitled "Structure-function relationship of clostridial neurotoxins" at the Department of Chemistry, UMass Boston, February 27, 1996.
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Presentation entitled “Partial nucleotide sequence of cinnamonin from Phytophthora cinnamomin pathogen of cranberry plants” at the Annual meeting of Cranberry Growers Association, March 1996, Taunton, MA.
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Presentation entitled "Fourier transform infrared spectroscopic analysis of protein structure and adsorption to solid surface" at the '96 Annual Meeting of the Korean Society of Photoscience, Korea, June 6-8, 1996.
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Presented a seminar entitled "Spectroscopic analysis of clostridial toxins" at the Department of Chemistry, University of Rhode Island, September 20, 1996.
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Presented a seminar entitled "Spectroscopic analysis of structure-function of botulinum and tetanus neurotoxins" at Department of Chemistry, Boston University on October 30, 1996.
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Presentation entitled " Botulinum neurotoxin complex and neurotoxin associated proteins (NAPs)" at the 1996 Meeting of Interagency Botulism Research Coordination Committee, Frederick, MD, November 6-8, 1996.
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Presented an invited seminar entitled "Thou sword turned into plowshare" at the Department of Chemistry, Merrimack College, February 26, 1997.
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Presented an invited seminar entitled "Cranberry and regulation of anthocyanin biosynthesis" at the Agricultural Research Division, Ocean Spray, Middleboro, April 17, 1997.
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Presentation entitiled "Development of active student participation as a method to instill favorable attitude for chemistry learning in non-science major students" at 29th Central Regional Meeting, Amercan Chemical Society, May 28-30, 1997.
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Presentation entitled "Molecular composition and topography of neurotoxin associated proteins (NAPs) of botulinum neurotoxin complex" at the Second International Meeting on the Molecular Genetics and Pathogenesis of the Clostridia, Seillac, Onzain, France, June 22-25, 1997.
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Presentation entitled "Teaching biochemistry laboratory course by using integrated research on xenobiotic detoxifying enzyme as an example" at the 214th National Meeting of American Chemical Society, September 7-11, 1997.
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Presentation entitled "Structure-function relationship of a novel type E botulinum neurotoxin complex" at the 1997 Meeting of Interagency Botulism Research Coordinating Committee. Nov. 11-14, 1997, Bethesda, Maryland.
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Presented an invited seminar entitled "Optical Fiber Biosensor Detection of Toxic Proteins " at the Department of Chemistry, UMass Lowell, February 2, 1998.
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Presented an invited seminar entitled "How Does a Bacterium Design the Most Poisonous Poison? How Does It Work? " at the Zoology Department, Brigham Young University, Provo, UT, March 12, 1998.
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Presented an invited seminar entitled "Critical Factors in Cranberry Color Development " at the Research and Development Division, Ocean Spray, Middleboro, March 20, 1998.
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Presented a seminar entitled " Structure Function Relationship of Botulinum Neurotoxin Associated Proteins", at the IPSEN-Speywood, Ltd., Berkshire, United Kingdom, June 30, 1998.
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Presented an invited seminar entitled "Debating the relevance of chemistry to non-science majors" at the 216th National Meeting of the American Chemical Society, Boston, MA, August 23-27, 1998.
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Presented an invited seminar entitled Overview of the IR spectroscopy of proteins at the 216th National Meeting of the American Chemical Society, Boston, MA, August 23-27, 1998.
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Presented an invited seminar entitled "Infrared analysis of biomacromolecules for their structure-function analysis" at the Department of Chemistry, Renselaer Polytechnic Institute, Troy, NY, October 7, 1999.
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Presented an invited seminar entitled " Infrared spectroscopic analysis of protein structure-function" at Amgen Corp, Thousand Oaks, CA, October 22, 1999.
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Presented an invited seminar entitled "The complex nature of the most poisonous poison: the Clostridium botulinum agents and reagents" at Allergan Corp., Irvine, October 21, 1999.
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Presented an invited seminar entitled "Glutathione-S-transferase as a major xenobiotic metabolism enzyme in animal, plant and microbial organisms" at Bridgewater State College, Bridgewater, MA, November 4, 1999.
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Presented a seminar entitled "Molecular basis of the unique endopeptidase activity of botulinum neurotoxin: role of dynamic structure" at the International Conference 1999 on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, Orlando, FL, November 16-18, 1999.
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Presented a seminar entitled "Analysis of Botulinum Neurotoxin Complex, at the IPSEN-Speywood, Ltd., Berkshire, United Kingdom, December 8, 1999.
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Presented a seminar entitled "Chemical and Environmental Research Approaches in the United States" at Government Postgraduate College, Hoshangabad, India, December 17, 1999.
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Presented a seminar entitled " Molecular Mechanism of the Most Poisonous Poison" at Jawaharlal Nehru University, New Delhi, India, January 17, 2000.
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Presented a seminar entitled " Summary of Research on Cranberry Root Rot and Anthocyanin Biosynthesis" at the Ocean Spray Cranberries, Inc., Lakeville-Middleboro, April 13, 2000.
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Presented a seminar entitled " Botulinum Toxin" at the DRDE, Gwalior, India, December 5, 2000.
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Presented a seminar entitled " Everybody is a Scientist" at the Kriyayoga Research Institute, New Jhunsi, Allahabad, India, July 9, 2001.
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Presented a seminar entitled " Creation of a Scientific Field" at Rani Durgawati University Jabalpur, India, July 25, 2001.
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Presented a seminar entitled " Use of Computer in Teaching and Learning in USA" at Rani Durgawati University Jabalpur, India, July 25, 2001.
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Presented a seminar entitled "Unique Structural Features of Botulinum Neurotoxin Required for Its Endopeptidase Activity" at the 38th Meeting of Interagency Botulism Research Coordinating Committee, October 17-19, 2001, Easton, Maryland.
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Presented a seminar entitled " Intimate Details of the Most Poisonous Poison" at the St. Mary College, MD, October 19, 2001.
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Presented a seminar entitled "Insight into the Inner Workings of the Most Poisonous Poison and Class Bioterror Agent" at Worcester Polytechnic Institute, Worcester, MA, October 9, 2002.
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Presented a seminar entitled "Protein Structure, Neurotoxins and Mysteries of Neuronal Mechanisms" to the Biochemistry class at Worcester Polytechnic Institute, Worcester, MA, October 9, 2002.
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Seminar entitled "Current and Unsettle Issues in the Molecular Action of Botulinum Neurotoxin." POC Frank Lebeda, Headquarters Conference Room, 1100 – 1200. December 19, 2002.
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Seminar entitled "Intimate Details of the Most Poisonous Poison on the Earth and Class A Bioterror Agent" at the School of Life Sciences, Jawaharlal Nehru University, New Delhi, December 30, 2002.
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Seminar entitled "Food Pathogens and Biosensor’ at Teachers" Training School, Jawaharlal Nehru University, New Delhi, January 2, 2003.
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Seminar entitled "Science of Philosophy and Indic Traditions" at the Center for Philosophy, Jawaharlal Nehru University, New Delhi, January 2, 2003.
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Seminar entitled "The Real Science of Life" at the National Cadet Corp, University of Allahabad, India, January 20, 2003.
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Seminar entitled "Kriyayoga and Scientific Way of Building a Universal Life" at the Nirala House, University of Allahabad, India, January 27, 2003.
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Seminar entitled "Inner Workings and Outward Effects of the Most Poisonous Poison", IPSEN Ltd., Slough, Berkshire, UK, January 30, 2003.
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Seminar entitled "Current and Unsettled Issues in Molecular Steps in Botulinum Action." Clostridia 03 Pathogenesis, Marine Biology Laboratory Woods Hole, Massachusetts, April 29, 2003.
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Seminar entitled "Inside Biological Stories of the Most Poisonous Bioterror Agent", Department of Pathology, University of Connecticut at Storrs, January 29, 2004.
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Seminar entitled "How Food Makes Everyone a Real Scientist", The Consortium for the Advancement of Teaching, Learning, and Scholarship (CATLS), UMass Dartmouth, September 14, 2004.
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Seminar entitled "Variation in endopeptidase activity of botulinum neurotoxins with their molecular forms", New England Regional Center of Excellence for Biodefense and Emerging Infectious Diseases (NERCE/BEID), First Annual Retreat New England Center, Durham, NH, September 19-20, 2004.
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Seminar entitled "Structural Variations Governing the Endopeptidase Activity of Different Seroptypes of Botulinum Neurotoxins", IBRCC 04, October 26-29, 2004.
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Seminar entitled "Biodefense and biotechnology research at UMass Dartmouth", New Bedford Mother’s Club, November 10, 2004.
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Seminar entitled "A Journey through the "Diversiland" of India", UMass Dartmouth Library Associates, December 5, 2004.
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Seminar entitled, "Structure, function, and genomics of botulinum neurotoxin and neurotoxin associated proteins", Yang Ming University, Taipei, March 13, 2005.
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Seminars entitled "India, Yoga and Diversity" presented to UMD’s Spotlight students on April 7 and 14, 2005.
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Seminar entitled "Yoga: its beginning and the benefits", was presented to UMass Dartmouth Library Associates, December 5, 2005.
Teaching Experience
COURSES TAUGHT/TEACHING:Graduate:
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Physical Biochemistry (6 semesters)
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Biophysical Techniques (6 semesters)
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Biochemistry II (1 semester)
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Biological Spectroscopy (3 semesters)
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Fluorescence Spectroscopy for Biochemists (1 semester)
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Chemistry of Mind (3 semesters)
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Graduate Seminar (1 semester)
Undergraduate:
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Undergraduate seminar (2 semesters)
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General Chemistry I (1 semester)
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General Chemistry II (5 semesters)
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General Chemistry Laboratory (7 semesters)
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Biochemical Techniques (9 semesters)
Research Experience
1979-1983: Structure-function studies of chloroplast membranes, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
1983-1987: Molecular topography and binding properties of phytochrome and other tetrapyrrolic proteins, Department of Chemistry, Texas Tech University.
1987-1990: Structure-function studies of botulinum, tetanus and staphylococcal toxins, Food Research Institute, University of Wisconsin, Madison.
1990-present: Molecular mode of action of botulinum and tetanus neurotoxins; molecular basis of enzymatic activity in organic solvents; Department of Chemistry, University of Massachusetts Dartmouth.
1999-present: Science of philosophy and its relationship to ancient and modern society
Membership in Professional Societies
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American Society for Biochemistry and Molecular Biology
(1990-present)
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American Association for the Advancement of Science (1988-present)
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American Chemical Society (1988-present)
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American Society for Microbiology (1995-present)
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American Society for Photobiology (1983-1993)
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International Society on Toxinology (1988-present)
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New York Academy of Sciences (1991-present)
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Society for Applied Spectroscopy (1990-present)
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Sigma Xi (1992-present)
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The Protein Society (1990-present)
Last Updated On: 2/20/07