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Alex J. Fowler, Ph.D.

Alex J. FowlerProfessor

  • Ph.D. in Mechanical Engineering, Duke University, 1993
  • B.A. in Philosophy, Wesleyan University, 1987

Contact information

  • Send Email
  • Phone: 508.999.8542
  • Fax: 508.999.8881
  • Office: Gr II, Room 116

Biography

  • Chairperson of Mechanical Engineering
  • Professor of Mechanical Engineering at UMass Dartmouth, 2007-present
  • Faculty Researcher at the Center for Engineering in Medicine, Massachusetts General Hospital
  • Research Fellow, Harvard University, Department of Surgery, Massachusetts General Hospital

Areas of interest

  • Bio-active materials
  • Bioengineering
  • Cryopreservation
  • Thermal Fluids

Selected publications

Fowler AJ and Bejan A, 1991, "The effect of shrinkage on the cooking of meat," International Journal of Heat and Fluid Flow, v. 12, pp. 375-383.

Fowler AJ and Bejan A, 1993, "Contact melting during sliding on ice," International Journal of Heat and Mass transfer, v. 36, no. 5, pp. 1171-1179.

Lim JS, Fowler AJ and Bejan A, 1993, "Porous medium model for a space filled with a fluid and fibers coated with a phase change material," Journal of Heat Transfer, v. 115, pp. 1044-1050.

Fowler AJ and Bejan A, 1994, "Correlation of optimal sizes of bodies with external forced convection heat transfer," International Communications in Heat and Mass Transfer, v. 21, pp. 17-27.

Fowler AJ and Bejan A, 1994, "Forced convection in banks of inclined cylinders at low Reynolds numbers," International Journal of Heat and Fluid Flow, v. 15, pp. 90-99.

Fowler AJ and Bejan A, 1995, "Forced convection from a surface covered with flexible fibers," International Journal of Heat and Mass Transfer, v. 38, pp. 767-777.

Bejan A, Fowler AJ and Stenescu G, 1995, "The optimal spacing between horizontal cylinders in a fixed volume cooled by natural convection," International Journal of Heat and Mass Transfer, v. 38, pp. 2047-2055.

Stenescu G, Fowler AJ and Bejan A, 1996, "The optimal spacing of cylinders in free-stream cross-flow forced convection," International Journal of Heat and Mass Transfer, v. 39, pp. 311-317.

Fowler AJ, Ledezma GA and Bejan A, 1997, "Optimal geometric arrangement of staggered plates in forced convection," International Journal of Heat and Mass Transfer, v. 40, pp. 1795-1805.

Bieganski RM, Fowler A, Morgan JR and Toner M, 1998, “Stabilization of active recombinant retro-viruses in amorphous dry state with trehalose,” Biotechnology Progress., v. 14, pp. 615-620.

Fowler AJ and Toner M, 1998, “Prevention of hemolysis in rapidly frozen erythrocytes by using a laser pulse,” Annals of the New York Academy of Science, v. 858, pp. 245-252.

Eroglu A., Russo MJ, Bieganski R, Fowler AJ, Cheley S, Bayley H and Toner M, 2000, “Intracellular trehalose improves the survival of cryopreserved mammalian cells, “Nature Biotechnology, v. 18, pp. 163-167.

Fowler AJ and Menguc MP, 2000, “Propagation of focused and multi-beam laser energy in biological tissue,” Journal of Biomechanical Engineering, v. 122, pp. 534-540.

Fowler AJ, 2000, “Selective photothermolysis in skin using subcutaneous optical fibers”, Lasers in Surgery and Medicine, v. 27, pp. 10-17.

Chen T, Acker JP, Eroglu A. Cheley S, Bayley H, Fowler AJ And Toner M, 2001, “Beneficial effect of intracellular trehalose on the membrane integrity of dried mammalian cells,” Cryobiology, v. 43, pp. 168-181.

Affonce DA and Fowler AJ, 2002, “The effect of thermal lensing during selective photothermolysis,” Journal of Quantitative Spectroscopy and Radiative Transfer, v. 73, pp. 473-479.

Reuss JD, Fowler AJ, Kim YK and Lewis A., 2002, “Manufacture of thick cross-section composites using a pre-catalyzed fabric technique,” Journal of Composite Materials, v. 36, pp. 1367-1379.

Acker JP, Fowler AJ, Lauman B, Cheley S And Toner M, 2002, “Survival of desiccated mammalian cells: beneficial effects of isotonic media,” Cell Preservation Technology, v.1, pp. 129-140.

Acker JP, Lu XM, Young V, Cheley S, Bayley H, Fowler A, Toner M,2003, “Measurement of trehalose loading of mammalian cells porated with a metal-actuated switchable pore,” Biotechnol Bioeng, v. 82; pp. 525-32.

Sugimachi K, Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M, 2004, “Long-term function of cryopreserved rat hepatocytes in a coculture system,” Cell Transplantation, v. 13, pp. 187-195.

Sosef MN, Baust JM, Sugimachi K, Fowler A, Tompkins RG, Toner M., 2005, Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function,” Ann. Surg, v. 241, pp. 125-133.

Fowler A and Toner M, 2005, “Cryo-injury and biopreservation,” (review) Annals of NY Acad of Sci, v. 1066, pp. 119-135.

Chen B, Fowler AJ and Bhowmick S, 2006, “Forced and natural convective drying of trehalose/water thin films: implication in the desiccation preservation of mammalian cells,” Journal of Biomechanical Engineering, v. 128, pp. 335-345.

Stacy R, Eroglu A, Fowler AJ, Biggers J and Toner M, 2006, “Thermal characterization of Nakagata’s mouse sperm freezing protocol,” Cryobiology, v. 52, pp. 99-107.

He X, Fowler AJ and Toner M, 2006, “Water Activity and Mobility in Solutions of Glycerol and Small Molecular Weight Sugars: Implication for Cryo- and Lyo- Preservation,” Journal of Applied Physics, v. 100, 074702

He X, Amin AA, Fowler AJ and Toner M, 2006, “Thermally induced introduction of trehalose into primary rat hepatocytes,” Cell Preservation Technology, v. 4, pp. 178-187.

Coskuntuna E, Fowler AJ, and Warner S, 2007, “Fibrous Structures with designed wicking properties,” Text. Res. J., v. 77, pp. 256-264

Green JE, Sitaula R, Fowler A, Toner M and Bhowmick S, 2007, “Enthalpic relaxation of convectively desiccated trehalose-water glasses,” Thermochemica Acta,, v. 453, pp. 1-8.

Reategui E. and Fowler AJ, 2008, “Desiccation of nucleated mammalian cells in nano-liter droplets,” Chemical Engineering Research and Design, v. 86, pp. 1187-1195.

He X., Fowler AJ, Menze M, Hand S and Toner M, 2008, “Desiccation kinetics and biothermodynamics of glass forming trehalose solutions in thin films,” Annals of Biomedical Engineering, v. 36, pp. 1428-1439.

He X, Park EY, Fowler A, Yarmush ML and Toner M, 2008, “Vitrification by ultra-fast cooling at low concentrations of cryoprotectants in a quartz micro-capillary: a study using murine embryonic stem cells,” Cryobiology, v. 56, pp. 223-232.

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