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CATEGORIES:College of Engineering,Thesis/Dissertations
DESCRIPTION:Advisors: Dr. Qinguo Fan and Mr. Jones Chang Committee Members:
  Mr. Jones Chang, and Drs. Qinguo Fan, Caiwei Shen, Chen-Lu Yang Abstract:
   The aim of this research is to produce the enzyme bilirubin oxidase thr
 ough stress-induced expression in Bacillus subtilis and to evaluate its ap
 plication as a cathodic biocatalyst for the oxygen reduction reaction in a
  hybrid hydrogen fuel cell. The study focuses on identifying ideal conditi
 ons to enhance enzymatic activity and operational stability under electroc
 hemical conditions relevant to fuel cell operation. The sources of cellula
 r stress in this study will be nitrogen starvation and the presence of cop
 per ions in growth media, both of which have been linked to increased Bili
 rubin Oxidase activity. In addition, graphene oxide will be employed as a 
 conductive interfacial material to improve enzyme immobilization, orientat
 ion, and utilization on carbon fiber electrodes. Owing to its high specifi
 c surface area, excellent biocompatibility, and abundance of functionaliza
 ble oxygen-containing groups, graphene oxide facilitates strong enzyme–e
 lectrode interactions and promotes favorable catalytic orientation for eff
 icient electron transfer. The synergistic integration of bilirubin oxidase
 , graphene oxide, and carbon fiber will improve cathodic performance while
  maintaining long-term stability of the system. Ultimately, this work seek
 s to advance the development of efficient and durable bio-based cathodes f
 or fuel cell applications.\nEvent page: https://www.umassd.edu/events/cms/
 bmb-ms-thesis-proposal-presentation-by-john-dalton.php
X-ALT-DESC;FMTTYPE=text/html:<html><body><p><strong>Advisors:</strong> Dr. 
 Qinguo Fan and Mr. Jones Chang</p>\n<p><strong>Committee Members:</strong>
  Mr. Jones Chang\, and Drs. Qinguo Fan\, Caiwei Shen\, Chen-Lu Yang</p>\n<
 p><strong>Abstract: </strong></p>\n<p>The aim of this research is to prod
 uce the enzyme bilirubin oxidase through stress-induced expression in Baci
 llus subtilis and to evaluate its application as a cathodic biocatalyst fo
 r the oxygen reduction reaction in a hybrid hydrogen fuel cell. The study 
 focuses on identifying ideal conditions to enhance enzymatic activity and 
 operational stability under electrochemical conditions relevant to fuel ce
 ll operation. The sources of cellular stress in this study will be nitroge
 n starvation and the presence of copper ions in growth media\, both of whi
 ch have been linked to increased Bilirubin Oxidase activity. In addition\,
  graphene oxide will be employed as a conductive interfacial material to i
 mprove enzyme immobilization\, orientation\, and utilization on carbon fib
 er electrodes. Owing to its high specific surface area\, excellent biocomp
 atibility\, and abundance of functionalizable oxygen-containing groups\, g
 raphene oxide facilitates strong enzyme–electrode interactions and promo
 tes favorable catalytic orientation for efficient electron transfer. The s
 ynergistic integration of bilirubin oxidase\, graphene oxide\, and carbon 
 fiber will improve cathodic performance while maintaining long-term stabil
 ity of the system. Ultimately\, this work seeks to advance the development
  of efficient and durable bio-based cathodes for fuel cell applications.</
 p><p>Event page: <a href="https://www.umassd.edu/events/cms/bmb-ms-thesis-
 proposal-presentation-by-john-dalton.php">https://www.umassd.edu/events/cm
 s/bmb-ms-thesis-proposal-presentation-by-john-dalton.php</a></a></p></body
 ></html>
DTSTAMP:20260310T051131
DTSTART;TZID=America/New_York:20260227T140000
DTEND;TZID=America/New_York:20260227T150000
LOCATION:Textiles 219
SUMMARY;LANGUAGE=en-us:BMB MS Thesis Proposal Presentation by John Dalton
UID:18334cbb3d8b30a493f15e318609077d@www.umassd.edu
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