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CATEGORIES:College of Arts and Sciences,Thesis/Dissertations
DESCRIPTION:Advisor: Dr. Erin Bromage Committee members: Dr. Genevieve Koza
 k, Dr. Katrina Velle, Dr. Michael Sheriff Abstract: Seasonal changes in te
 mperature and photoperiod shape immunity across vertebrates, yet their int
 eractive effects on adaptive immune responses in ectotherms remain poorly 
 understood. In teleost fish, temperature is a well-established regulator o
 f adaptive immunity, but the contribution of photoperiod—and its interac
 tion with temperature—remains unclear. This knowledge gap has important 
 implications for predicting immune responses under climate change and opti
 mizing environmental conditions in aquaculture. Using a fully factorial ex
 perimental design, rainbow trout (Oncorhynchus mykiss) were acclimated to 
 two temperatures (10°C and 15°C) and three photoperiods (8L:16D, 12L:12D
 , and 16L:8D) before immunization with a defined antigen. Temperature emer
 ged as the primary driver of adaptive immunity, with fish held at 15°C ex
 hibiting faster and stronger B-cell responses, higher serum IgM concentrat
 ions, and greater antigen-specific antibody titers than fish maintained at
  10°C. In contrast, photoperiod exerted more modest and context-dependent
  effects, with short-day conditions enhancing specific antibody production
  primarily in immunized fish.\nEvent page: https://www.umassd.edu/events/c
 ms/7-3-26-regulation-of-b-cell-mediated-adaptive-immunity-in-r.php
X-ALT-DESC;FMTTYPE=text/html:<html><body><p>Advisor: Dr. Erin Bromage</p>\n
 <p>Committee members: Dr. Genevieve Kozak\, Dr. Katrina Velle\, Dr. Michae
 l Sheriff</p>\n<p>Abstract:</p>\n<p>Seasonal changes in temperature and ph
 otoperiod shape immunity across vertebrates\, yet their interactive effect
 s on adaptive immune responses in ectotherms remain poorly understood. In 
 teleost fish\, temperature is a well-established regulator of adaptive imm
 unity\, but the contribution of photoperiod—and its interaction with tem
 perature—remains unclear. This knowledge gap has important implications 
 for predicting immune responses under climate change and optimizing enviro
 nmental conditions in aquaculture.</p>\n<p>Using a fully factorial experim
 ental design\, rainbow trout (Oncorhynchus mykiss) were acclimated to two 
 temperatures (10°C and 15°C) and three photoperiods (8L:16D\, 12L:12D\, 
 and 16L:8D) before immunization with a defined antigen. Temperature emerge
 d as the primary driver of adaptive immunity\, with fish held at 15°C exh
 ibiting faster and stronger B-cell responses\, higher serum IgM concentrat
 ions\, and greater antigen-specific antibody titers than fish maintained a
 t 10°C. In contrast\, photoperiod exerted more modest and context-depende
 nt effects\, with short-day conditions enhancing specific antibody product
 ion primarily in immunized fish.</p><p>Event page: <a href="https://www.um
 assd.edu/events/cms/7-3-26-regulation-of-b-cell-mediated-adaptive-immunity
 -in-r.php">https://www.umassd.edu/events/cms/7-3-26-regulation-of-b-cell-m
 ediated-adaptive-immunity-in-r.php</a></a></p></body></html>
DTSTAMP:20260617T204248
DTSTART;TZID=America/New_York:20260703T120000
DTEND;TZID=America/New_York:20260703T130000
LOCATION:LIB-314
SUMMARY;LANGUAGE=en-us:Temperature and Photoperiod Regulation of B-Cell Med
 iated Adaptive Immunity in Rainbow Trout (Oncorhynchus mykiss): Implicatio
 ns for Aquaculture and Climate Change
UID:9fbefe495cab17bfd8c4d333a3c0246f@www.umassd.edu
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