BEGIN:VCALENDAR VERSION:2.0 X-WR-CALNAME:EventsCalendar PRODID:-//hacksw/handcal//NONSGML v1.0//EN CALSCALE:GREGORIAN BEGIN:VTIMEZONE TZID:America/New_York LAST-MODIFIED:20240422T053451Z TZURL:https://www.tzurl.org/zoneinfo-outlook/America/New_York X-LIC-LOCATION:America/New_York BEGIN:DAYLIGHT TZNAME:EDT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 DTSTART:19700308T020000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU END:DAYLIGHT BEGIN:STANDARD TZNAME:EST TZOFFSETFROM:-0400 TZOFFSETTO:-0500 DTSTART:19701101T020000 RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU END:STANDARD END:VTIMEZONE BEGIN:VEVENT CATEGORIES:College of Engineering,Lectures and Seminars DESCRIPTION:Topic: “Stretching the Basis of Life: Studying Drug-DNA Inter actions Using Optical Tweezers”  Abstract: Dual-beam optical tweezers u se two counter-propagating laser beams that are tightly focused to a singl e point, enabling the trapping and manipulation of microscopic objects. In our research, we use this technique to capture individual DNA molecules a nd investigate how current and prospective anticancer drugs interact with DNA. These studies help us understand the drugs' binding mechanisms, stren gths, and specific interactions at the single-molecule level. Biography: D r. Thayaparan Paramanathan (Dr. Thaya) is a biophysicist whose research co mbines advanced physics techniques with biological investigations at the s ingle-molecule level. He earned his B.S. in Physics with Honors from the U niversity of Jaffna, Sri Lanka, and his Ph.D. in Physics from Northeastern University, where he investigated anticancer drug–DNA interactions usin g optical tweezers. He subsequently completed postdoctoral research at Bra ndeis University, studying biomolecular interactions using Total Internal Reflection Fluorescence (TIRF) Microscopy. At Bridgewater State University (BSU), Dr. Thaya established the Single Molecule Biophysics Laboratory, w here he mentors undergraduate researchers in investigating anticancer drug –DNA interactions. His research publications have received over 800 cita tions, and a recent paper coauthored with BSU undergraduates was featured in a special issue of Biophysical Journal dedicated to the “Biophysics o f Cancer.” Since joining BSU in 2014, Dr. Thaya has demonstrated a stron g commitment to undergraduate teaching, research, and mentorship. He coord inated BSU’s Adrian Tinsley Summer Research Program (2017–2020) and ha s received multiple teaching and mentoring awards, including the prestigio us Excellence in Undergraduate Education Award from the Biophysical Societ y for his outstanding contributions to undergraduate education and researc h in biophysics.  NOTE: All ECE Graduate Students are ENCOURAGED to atten d. All interested parties are invited to attend. Open to the public.  *Fo r further information, please contact Dr. Ana Doblas via email at adoblas@ umassd.edu.\nEvent page: https://www.umassd.edu/events/cms/11-13-26-dr-tha yaparan-paramanathan-professor-of-physics.php X-ALT-DESC;FMTTYPE=text/html:

Topic: “Stretching the Basis of Life: Studying Drug-DNA Interactions Using Optical Tweezers” 

\n< p>Abstract: Dual-beam optical tweezers use two counter-propagating laser b eams that are tightly focused to a single point\, enabling the trapping an d manipulation of microscopic objects. In our research\, we use this techn ique to capture individual DNA molecules and investigate how current and p rospective anticancer drugs interact with DNA. These studies help us under stand the drugs' binding mechanisms\, strengths\, and specific interaction s at the single-molecule level.

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Biography: Dr. Thayaparan Paramana than (Dr. Thaya) is a biophysicist whose research combines advanced physic s techniques with biological investigations at the single-molecule level. He earned his B.S. in Physics with Honors from the University of Jaffna\, Sri Lanka\, and his Ph.D. in Physics from Northeastern University\, where he investigated anticancer drug–DNA interactions using optical tweezers. He subsequently completed postdoctoral research at Brandeis University\, studying biomolecular interactions using Total Internal Reflection Fluores cence (TIRF) Microscopy. At Bridgewater State University (BSU)\, Dr. Thaya established the Single Molecule Biophysics Laboratory\, where he mentors undergraduate researchers in investigating anticancer drug–DNA interacti ons. His research publications have received over 800 citations\, and a re cent paper coauthored with BSU undergraduates was featured in a special is sue of Biophysical Journal dedicated to the “Biophysics of Cancer.” Si nce joining BSU in 2014\, Dr. Thaya has demonstrated a strong commitment t o undergraduate teaching\, research\, and mentorship. He coordinated BSU ’s Adrian Tinsley Summer Research Program (2017–2020) and has received multiple teaching and mentoring awards\, including the prestigious Excell ence in Undergraduate Education Award from the Biophysical Society for his outstanding contributions to undergraduate education and research in biop hysics.

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 NOTE: All ECE Graduate Students are ENCOURAGED to attend . All interested parties are invited to attend. Open to the public.

\n< p> *For further information\, please contact Dr. Ana Doblas via email at adoblas@umassd.edu.

Event page: https ://www.umassd.edu/events/cms/11-13-26-dr-thayaparan-paramanathan-professor -of-physics.php

DTSTAMP:20261109T210240 DTSTART;TZID=America/New_York:20261113T140000 DTEND;TZID=America/New_York:20261113T150000 LOCATION:Science & Engineering Building (SENG), Room 222 SUMMARY;LANGUAGE=en-us:Speaker: Dr. Thayaparan Paramanathan, Professor of P hysics, Photonics and Optical Engineering UID:92a11857231370058c2c7ff25de8b2b3@www.umassd.edu END:VEVENT END:VCALENDAR