Education

Research

Research interests

• Bioanalytical and biophysical chemistry
• Protein chemistry
• Drug formulation
• Pharmaceutical biotechnology

Select publications

• Cai S., Singh B. R. (2004).
  A Distinct Utility of Amide III Infrared Band for Secondary Structure Estimation of Aqueous Protein Solutions Using Partial Least Square Methods
  Biochemistry, 43, 2541–2549.
  
• Poirier M. A., Li H., Macosko J., Cai S., Amzel M., Ross C. A. (2002).
  Huntingtin Spheroids and Protofibrils as Precursors in Polyglutamine Fibrilization
  Journal of Biological Chemistry (J. Biol. Chem.), 277, 41032–41037.
  
• Cai S., Singh B. R. (2001).
  Role of the Disulfide Cleavage Induced Molten Globule State of Type A Botulinum Neurotoxin in Its Endopeptidase Activity
  Biochemistry, 40, 15327–15333.
  
• Cai S., Singh B. R. (2001).
  A Correlation between Differential Structural Features and the Degree of Endopeptidase Activity of Type A Botulinum Neurotoxin in Aqueous Solution
  Biochemistry, 40, 4693–4702.
  
• Cai S., Singh B. R. (1999).
  Identification of β-turn and Random Coil Amide III Infrared Bands for Secondary Structure Estimation of Proteins
  Biophysical Chemistry (Biophys. Chem.), 80, 7–20.
  

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