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faculty
Shuowei Cai, PhD
Professor
Chemistry & Biochemistry
Contact
508-999-8807
508-999-8451
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Violette Research E201
Education
| 2001 | University of Massachusetts Amherst | PhD |
| 1998 | University of Massachusetts Dartmouth | MS |
| 1993 | Nankai University, China | MS |
| 1990 | Nankai University, China | BS |
Teaching
Programs
Programs
Teaching
Courses
Students will integrate knowledge that they have gained throughout the major and the University Studies curriculum to perform a capstone research project. This will include a lecture component on presenting data in addition to the major laboratory research focus.
Students will integrate knowledge that they have gained throughout the major and the University Studies curriculum to perform a capstone research project. This will include a lecture component on presenting data in addition to the major laboratory research focus.
Physico-chemical principles governing structures of biological macromolecules. Topics include energetics and kinetics of biochemical processes, including binding, catalysis, diffusion/transport, and folding/unfolding; behavior of macromolecules in aqueous medium; and application of spectroscopic methods in biochemistry.
Original chemical research and preparation of thesis. Required for Plan A master's degree. Graded P/F.
Original chemical research and preparation of thesis. Required for Plan A master's degree. Graded P/F.
Research
Research interests
- Bioanalytical and biophysical chemistry
- Protein chemistry
- Drug formulation
- Pharmaceutical biotechnology
Select publications
- Cai S., Singh B. R. (2004).
A Distinct Utility of Amide III Infrared Band for Secondary Structure Estimation of Aqueous Protein Solutions Using Partial Least Square Methods
Biochemistry, 43, 2541–2549. - Poirier M. A., Li H., Macosko J., Cai S., Amzel M., Ross C. A. (2002).
Huntingtin Spheroids and Protofibrils as Precursors in Polyglutamine Fibrilization
Journal of Biological Chemistry (J. Biol. Chem.), 277, 41032–41037. - Cai S., Singh B. R. (2001).
Role of the Disulfide Cleavage Induced Molten Globule State of Type A Botulinum Neurotoxin in Its Endopeptidase Activity
Biochemistry, 40, 15327–15333. - Cai S., Singh B. R. (2001).
A Correlation between Differential Structural Features and the Degree of Endopeptidase Activity of Type A Botulinum Neurotoxin in Aqueous Solution
Biochemistry, 40, 4693–4702. - Cai S., Singh B. R. (1999).
Identification of β-turn and Random Coil Amide III Infrared Bands for Secondary Structure Estimation of Proteins
Biophysical Chemistry (Biophys. Chem.), 80, 7–20.