Christopher Brigham, PhD

Chemical principles and key concepts for bioengineers including chemical nomenclature, chemical syntheses, nucleic acid and protein chemistry, enzymology, metabolism, and others. Students will utilize the methods and concepts taught in this course for problem solving in biotechnology, biomanufacturing and the biopharmaceutical fields. This course also discusses manufacturing, validating, and using drugs, plastics, gels, polymers and fuels for biotechnology industry.

Chemical principles and key concepts for bioengineers including chemical nomenclature, chemical syntheses, nucleic acid and protein chemistry, enzymology, metabolism, and others. Students will utilize the methods and concepts taught in this course for problem solving in biotechnology, biomanufacturing and the biopharmaceutical fields. This course also discusses manufacturing, validating, and using drugs, plastics, gels, polymers and fuels for biotechnology industry.

Computer-based modeling of biological systems and examination of signal characteristics from biosystems and biomedical instrumentation. Use of object-oriented computer modeling (e.g., Python and Biopython) to examine behavior of cells and other biosystems, including transcription and translation, biological sequence comparison, and signal processing. Computational signals and systems labs will be assigned to analyze biomedical signals and other biosystem aspects using tools like MatLab and Simulink. The course focuses on computer literacy and enhancement of proficiency in using modeling and simulation tools.

A detailed overview of the important aspects of the emerging field of synthetic biology. The field of synthetic biology spans the boundaries of biology, chemistry and engineering with the goal of engineering biomolecular systems and cellular capabilities for a variety of applications. This course will cover three foundational parts of synthetic biology, including the biological background of molecular genetics, gene regulation, experimental methods for genetic circuit construction and networks/network modeling. Successful applications of synthetic biology in biofuels, biomedicine and other areas will be discussed in detail to demonstrate the potential impact of the field in these areas.

Professional and management activities of project engineering as a two course sequence. Students working in teams will integrate their learning by selecting a senior Bioengineering design project, leading to a written and oral presentation of a project proposal. Intellectual property rights, ethics and economic issues, as well as applicable regulations will be considered.

Application of knowledge gained in various courses to the synthesis, analysis, and design of a system in a particular bioengineering field of interest selected by the student's team. The product proposed in BNG 497 will be built in BNG 498.

Application of knowledge gained in various courses to the synthesis, analysis, and design of a system in a particular bioengineering field of interest selected by the student's team. The product proposed in BNG 497 will be built in BNG 498.