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faculty
Lamya Karim, PhD
Associate Professor
Bioengineering
Contact
508-999-8560
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Education
| 2011 | Rensselaer Polytechnic Institute | PhD in Biomedical Engineering |
| 2007 | Stony Brook University | BE in Biomedical Engineering |
Teaching
- Biomechanics
- Mechanobiology
- Biomedical Devices
Teaching
Programs
Programs
Teaching
Courses
A culminating experience in which the student synthesizes his/her course knowledge and experimental skills into a brief but detailed experimental study, which also involves cross-field interdisciplinary cooperation. Although in some cases this project may be done individually under the supervision of one faculty member, it is expected that students will join in a team-based, collaborative effort involving students from a number of different disciplines, post-doctoral fellows and industry representatives and with intercampus participation.
Introduction to principles of major biomedical devices. Course topics include rules and regulations for the design of biomedical devices, history of the devices, general design and operating principles, and related current research.
This course is a discussion of design of biomedical engineering devices and systems, laws and regulations applied to medical product development, manufacturing, testing, marketing, and post-marketing surveillance. This course provides an overview of regulatory affairs related to biomedical devices and a foundation to understand the regulations based on the US FDA requirements.
Introduction to principles of major biomedical devices. Course topics include rules and regulations for the design of biomedical devices, history of the devices, general design and operating principles, and related current research.
This course is a discussion of design of biomedical engineering devices and systems, laws and regulations applied to medical product development, manufacturing, testing, marketing, and post-marketing surveillance. This course provides an overview of regulatory affairs related to biomedical devices and a foundation to understand the regulations based on the US FDA requirements.
Research
Research awards
- $ 41,800 awarded by Massachusetts General Hospital | NIH for Pilot Awards Subproject Fund
- $ 2,577 awarded by Montana State University for AGE Assessment for Germ Free Study
Research
Research interests
- Biomechanics
- Mechanobiology
- Orthopedics
- Skeletal health
- Bone cell biology
Skeletal fragility in patients with type 2 diabetes is a growing public health issue. The prevalence of diabetes is increasing rapidly, and diabetics have three times greater fracture risk compared to non-diabetics. The causes of diabetic skeletal fragility are not well established, which makes it difficult for clinicians to make decisions regarding fracture prevention in this population. Numerous micro-scale changes may contribute to skeletal health issues in these patients. For instance, changes in bone matrix composition due to accumulation of non-enzymatic chemical crosslinks can lead to poor bone quality and in turn deteriorate bone’s mechanical integrity. These crosslinks can also lead to an increase in the formation of micro-scale damage within bone. Further, some patients have altered bone microarchitecture that could contribute to their increased fracture risk, and these microarchitectural changes may result from altered bone cell behavior. Thus, we aim to investigate the biomolecular and cellular mechanisms of skeletal fragility in diabetes and other major clinical conditions. The ultimate goal of our research is to help improve diagnostic methods for fracture risk assessment and clinical management of patients at risk for fracture.