ELEE Oral Comprehensive Exam for Doctoral Candidacy by Sofia Obando-Vasquez
Topic: Design and Implementation of a Super-Resolution Dual-Mode Microscope for Intensity and Quantitative Phase Imaging Tunable Across Multiple Objective Lenses
Abstract: Despite significant advances in optical microscopy, no single instrument currently enables super-resolution imaging of the same sample in both intensity and phase modalities simultaneously. This limitation restricts the comprehensiveness of sample analysis, as fluorescence-based super-resolution and quantitative phase imaging (QPI) provide complementary yet distinct information about specimens under study. Fluorescence super-resolution techniques allow visualization of specifically labeled structures beyond the diffraction limit, offering high molecular specificity. Quantitative phase imaging, in contrast, provides label-free, nanometer-scale sensitivity to optical path length variations, revealing morphological and dynamical properties of transparent samples without exogenous contrast agents. Integrating both modalities into a unified platform would enable a more complete characterization of biological and physical samples.
Advisor: Dr. Ana Doblas, Assistant Professor, Department of Electrical & Computer Engineering, UMASS Dartmouth
Committee Members: Dr. John Buck, Chancellor Professor, Dept. of Electrical & Computer Engineering, UMASS Dartmouth; Dr. Paul Gendron, Associate Professor, Dept. of Electrical & Computer Engineering, UMASS Dartmouth; Dr. Francisco Robles, Associate Professor, Wallace H. Coulter Dept. of Biomedical Engineering at the Georgia Institute of Technology and Emory University
NOTE: All ECE Graduate Students are ENCOURAGED to attend. All interested parties are invited to attend. Open to the public.
*For further information, please contact Dr. Ana Doblas via email at adoblas@umassd.edu
Lester W. Cory Conference Room, Science & Engineering Building (SENG), Room 213A
: Zoom Link: https://umassd.zoom.us/j/99662035631 Meeting ID: 996 6203 5631 Passcode: 811167
Ana Doblas
5089998471
adoblas@umassd.edu
https://umassd.zoom.us/j/99662035631