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Sankha Bhowmick, Ph. D.

Sankha Bhowmick

Associate professor

  • Ph. D in Mechanical Engineering, University of Minnesota, 2000
  • M.S. in Mechanical Engineering, Villanova University, 1996
  • B.S. in Mechanical Engineering, Jadavpur University, India, 1992

Contact information

  • Send Email
  • Phone: 508.999.8619
  • Fax: 508.999.8881
  • Office: Textiles Building, Room 210

Biography

Dr. Bhowmick obtained his undergraduate from Jadavpur University, Calcutta in 1992. He worked for Philips, India as a mechanization and maintenance engineer in the color television and audio equipment factory for two and a half years before coming to the US for his masters and Ph. D. His concentration in graduate studies was heat transfer and thermodynamics with a keen interest in their application in biomedical science. His Ph.D. dissertation was optimization of thermal therapy for treatment of prostate cancer. As a research fellow at Harvard Medical School, he has been trying to preserve mammalian cells, so that they can be kept in suspended animation for extensive time periods (months-years) and then revived for use when necessary.

The overarching theme of Prof. Bhowmick's work is studying heat, mass and chemical stresses in mammalian cells under altered environmental conditions. Currently, he is actively involved in developing nanofibrous scaffolds for various tissue engineering applications. One such application is the bioactive bandage for wound healing.

Areas of interest

  • Bioengineering
  • Cell and Tissue Engineering
  • Heat and mass transfer
  • MEMS
  • Thermal Sciences
  • Transport applications related to microfabrication

Selected publications

Journal publications

Bhowmick S., Khamis C. A., Bischof, J. C., 1998, "Response of a liver tissue slab to a hyperosmotic sucrose boundary condition: microscale cellular and vascular level effects," Ann. NY Acad.Sci., Vol. 858, pp. 147-62

Bhowmick, S., Swanlund, D. J., and Bischof, J. C., 2000, "Supraphysiological thermal injury in Dunning AT-1 prostate tumor cells," ASME J. Biomech., Engg, Vol. 122, pp. 51-59

Bhowmick, S., Lulloff, L., Swanlund D. J., Coad, J. E., Hoey, M. F., and Bischof, J. C., 2001, "Evaluation of thermal therapy in an animal model of prostate cancer using a wet electrode RF probe," Journal of Endourology. , Vol. 15-6, pp. 629-640.

Bhowmick, S., Hoffmann, N. E, and Bischof, J. C., 2002, “Thermal therapy of normal and tumor tissue in the dorsal skin flap chamber,” Microvascular Research , Vol. 64, pp. 170-173.

Chen, T., Bhowmick, S., Sputtek,A., Fowler,A. and Toner, M., 2002, "The Glass Transition Temperature of Mixtures of Trehalose and Hydroxyethyl Starch," Cryobiology, Vol. 44, pp. 301-306.

Bhowmick, S., Zhu, L., Mcginnins, L., Lawitts, J., Nath, B. D., Toner, M. and Biggers, J. D., 2003 “Preservation of Murine Spermatozoa Using Convective Drying at Ambient Temperature”, Biology of Reproduction, Vol. 68, pp. 1779-1786

Bhowmick, S., Coad, J. E., and Bischof, J. C., 2004 "In vitro thermal therapy in the Dunning AT-1 prostate tumor," International Journal of Hyperthermia Vol. 20-1, pp. 73-94.

Bhowmick, P., Coad, JE, Bhowmick, S., Pryor, JL, Larson, T, Rosette, J and Bischof, JC, 2004 “In vitro assessment of the efficacy of thermal therapy in human benign prostatic hyperplasia”, International Journal of Hyperthermia Vol. 20, No. 4, pp. 421–439.

Mcginnins, L , Zhu, L.,. Lawitts, J., Bhowmick, S., Toner, M. and Biggers, J. D., 2005 “Mouse sperm desiccated and stored in trehalose medium without freezing”, Biology of Reproduction, Vol 73, pp. 627-633

Chen, B., Fowler, A, and Bhowmick, S., 2006, “Forced and natural convective drying of trehalose/water thin films: Implication in the desiccation preservation of mammalian cells”, ASME Journal of Biomechanical Engineering, Vol. 128(3), pp. 335-346.

Sitaula, R., and Bhowmick, S., 2006 “A study of the Thermophysical Properties and Moisture Sorption Characteristics of Trehalose-PBS Glasses”, Cryobiology, Vol. 52, pp. 369-385.

Chen, M., Patra, P., Warner, S and Bhowmick, S., 2006, “Optimization of electrospinning process parameters for tissue engineering scaffolds,” Biophysical Reviews and Letters, Vol. 1(2), pp. 189-214.

Shah, B and Bhowmick, S., 2006, “Evaluation of Important Treatment Parameters in Supraphysiological Thermal Therapy of Human Liver Cancer HepG2 Cells,” Annals of Biomedical Engineering, Vol 34(6), pp. 1745-1757.

Chen, M., Patra, P., Warner, S and Bhowmick, S., 2007, “Role of fiber diameter in adhesion and proliferation of NIH 3T3 fibroblast on electrospun polycaprolactone (PCL) scaffolds,” Tissue Engineering, Vol. 13 (3), DOI: 10.1089/ten.2006.0205

Green JE, Sitaula R, Fowler AJ, Toner M and Bhowmick S., 2007, “Enthalpic Relaxation of Convective desiccated trehalose-water glasses”, Accepted for publication in Thermochimica Acta http://dx.doi.org/10.1016/j.tca.2006.10.014

Borgaonkar, P., Sharma, S., Chen, M, Bhowmick, S. and Schmidt, D. F., 2007, “Towards a Flexible, Biomimetic Approach to the Preparation of Polymer Scaffolds for Tissue Engineering” Accepted in Macromolecular Bioscience

Selected peer reviewed conference proceedings

Bhowmick, S., Branchi, C., Mcassey, Jr., E.V., and Gollin, M., 1996, " Heat transfer performance of engine coolants under sub-cooled boiling conditions," ASME ICE- Vol. 26- 2, pp. 53-59.

Bhowmick, S., Swanlund, D. J., and Bischof, J. C., 1998, “Supraphysiological thermal injury in Dunning AT-1 prostate tumor cells,” HTD-Vol. 362/BED-Vol. 40, Adv in Heat and Mass Transfer in Biotechnology, pp 77-78.

Bhowmick, S., Pedersen, J., and Bischof, J. C., 2000, “Investigation of Corneal/Scleral burning during cataract surgery,” HTD-Vol. 368/BED-Vol. 47, Adv. in Heat and Mass Transfer in Biotechnology, pp. 73-74.

Bhowmick, S. and Bischof, J. C., 2000, “Source terms in thermal therapy: A parametric study,” ASME HTD-368/BED-47, Adv. in Heat and Mass Transfer in Biotechnology, pp 161-168.

Bhowmick, S., Bhowmick, P., Coad, J. E. and Bischof, J. C., 2001, “ In vitro assessment of thermal therapy in Human BPH Tissue,” ,” Proceedings of IMECE 2001, New York, NY

Bhowmick, S., Nath, B. D., Biggers, J. D., and Toner, M., 2002, “ Thermostability studies of desiccated murine spermatozoa nuclear DNA to predict the beneficial effect of trehalose in long term storage,” Proceedings of IMECE 2002, New Orleans, LA.

Zhao, Z., Cusick, J., Fowler, A., Bhowmick, S., and Toner, M, 2003, “ Optimization And Storage Of Micro-Fabricated Skin Substitutes,” ASME Summer Bioengineering Conference, Miami, FL.

Wang, W., Bhowmick, S., Ellis, D., Warner, S., and Fowler, A., 2003, “Loading of Genetically Engineered Bacteria into Hollow Milkweed Fibers,” ASME Summer Bioengineering Conference, Miami, FL.

Green, J., Fowler, A., Toner, M. and Bhowmick, S., 2004, “A study of enthalpic relaxation of trehalose-water glasses,” Proceedings of IMECE 2004, Anaheim, CA.

Chen, B. and Bhowmick, S., 2004, “Modeling of convective drying of trehalose-water glasses,” Proceedings of IMECE 2004, Anaheim, CA.

Chen, M., Patra, P., Warner, S., and Bhowmick, S., 2005, “Development of a biodegradable nanofiber scaffold by optimization of electrospinning process parameters,” ASME Summer Bioengineering Meeting , Vail, CO.

Sitaula, R., and Bhowmick, S., 2005, “A study of the thermophysical and moisture sorption properties of trehalose glasses,” ASME Summer Bioengineering Meeting , Vail, CO.

Borgaonkar, P., Sharma, S., Schmidt, DF, Chen M., Bhowmick S, 2007, “ Preparation and characterization of polyester thermoset xerogels for tissue engineering scaffolds,” Society of Plastics Engineers Annual Technical Conference

Selected abstracts

Bhowmick, S., Lulloff, L., Swanlund D. J., Coad, J. E., Hoey, M. F., and Bischof, J. C., 1999, "Studies of thermal therapy in vivo using a wet electrode RF probe,” BMES/EMBS Conference, Atlanta, GA.

Bhowmick, S., Coad, J. E., and Bischof J. C.,2000, "In vitro thermal therapy in the Dunning AT-1 prostate tumor," Chicago 2000 World Congress of Medical Physics.

Hoffmann, N. E., Bhowmick, S. and Bischof, J. C.,2000, "Observation of vascular injury after hyperthermic injury in the dorsal skin flap chamber," Chicago 2000 World Congress of Medical Physics.

Devireddy, R. V., Bhowmick, S., Neidert, M.R., Tranquillo, R. T. and Bischof, J. C., 2000, “Determination of Loading and Unloading of Cryoprotective Agents in Tissues and Tissue-Equivalents, {Abstract # T12.43}, Annals of Biomedical Engineering 28 (Supp. 1), S-124.

Schmidlin, F., Bhowmick, S., Coad, J. E. and Bischof, J. C., 2001, “ In vitro and acute in vivo assessment of microwave thermal therapy in a porcine kidney model,” European Urology Conference

Bhowmick, S., Zhu, L., McGinnis, L., Lawitts, J., Nath, BD, Toner, M., Biggers, J. , “Beneficial Effect of Trehalose in the Desiccation of Murine Spermatozoa,” Cryo 2002, pp. 48.

Heat Sensitivity of Human Prostatic Tissue: Implications for Thermal Therapy. J.C. Bischof, P. Bhowmick J.E. Coad, S. Bhowmick, J. Pryor, T. Larson, J. de la Rosette XVIIIth European Association of Urology Congress. Madrid Spain, March 12-15 2003. (Best Poster Award in Session)

Chen, B., Fowler, A and Bhowmick, S., 2003, “Drying Kinetics Of Water/Sugar Mixtures,” Sigma Xi Poster Exhibition, 2003, UMass Dartmouth, N. Dartmouth, MA.

Zhao, Z., Fowler, A., Bhowmick, S., Ellis, D., Warner, S., Cusick, J., and Toner, M, 2003, “Deve

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